adherens junctions造句

• Intercalated discs are composed of gap junctions, adherens junctions and desmosomes, and are critical for the mechanical and electrical coupling of adjacent cardiomyocytes.
• EMT's important feature is the loss of membrane E-cadherin in adherens junctions, where ?-catenin may play a significant role.
• In addition to catenins and cadherins, PTPmu dephosphorylates PIPKI?90 and nectin-3 ( PVRL3 ) to stabilize E-cadherin-based adherens junctions.
• Knock-out of PLEKHA7 results in the loss of PDZD11 from epithelial adherens junctions, and this is rescued by the introduction of exogenous PLEKHA7.
• In cardiac muscle, beta-catenin localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocyte.
• However, immunoelectron microscopy indicates that paracingulin is not only localized in the TJ but also in the adherens junctions ( AJ ) depending on tissue type.
• In 2016, researchers found that PLEKHA7 recruits the small PDZ protein PDZD11 to adherens junctions, thus resulting in the stabilisation of nectins at adherens junctions.
• In 2016, researchers found that PLEKHA7 recruits the small PDZ protein PDZD11 to adherens junctions, thus resulting in the stabilisation of nectins at adherens junctions.
• Intercalated discs consist of three different types of cell-cell junctions : the actin filament anchoring adherens junctions, the intermediate filament anchoring desmosomes, and gap junctions.
• Further studies showed that cardiac fibers obtained from " JUP "-null embryonic mice had decreased passive compliance albeit normal attachment of sarcomeres to adherens junctions.
• Integrity of intercellular junctions is a major determinant of permeability of the endothelium, and the VE-cadherin-based adherens junction is thought to be particularly important.
• In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.
• This PTP was shown to function in the regulation of epithelial cell cell contacts at adherens junctions, as well as in the control of beta-catenin signaling.
• Additional malformation included reduced cytoskeletal rearrangement in order to properly couple the assembly of adherens junctions to the translocation of desmosome precursors in newly formed cell-cell junctions.
• Nectins are ubiquitously expressed and have adhesive roles in a wide range of tissues such as the adherens junction of epithelia or the chemical synapse of the neuronal tissue.
• Vinculin is associated with focal adhesion and adherens junctions, which are complexes that nucleate actin filaments and crosslinkers between the external medium, plasma membrane, and actin cytoskeleton.
• Plakoglobin is a cytoplasmic component of desmosomes and adherens junctions structures located within intercalated discs of cardiac muscle that function to anchor sarcomeres and join adjacent cells in cardiac muscle.
• Classical cadherins are important proteins for cells to bind in the body (   in vivo  ) where they commonly stabilize cell cell junctions known as adherens junctions.
• Although the precise details are much less clear, it appears that the same site is used by alpha-catenin when beta-catenin is localized to the adherens junctions.
• Cell cell adhesion complexes are essential for the formation of complex animal tissues . ?-catenin is part of a protein complex that form the so-called adherens junctions.